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Yinghong Ji

MD, PhD

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M.D, PH.D

Biography

Dr. Ji conducts basic and clinical research in the areas of cataracts, including age-related cataracts and congenital cataracts. She also performs several funded research projects to investigate the mechanisms and treatments for cataract from genomics, proteomics, and metabolomics, respectively.

 

Publications

1.     Exosomes from adipose-derived stem cells attenuate UVB-induced apoptosis, ROS, and the Ca2+ level in HLEC cells. Exp Cell Res. 2020 Nov 15;396(2):112321.

2.     TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox Biol. 2019 Apr; 22: 101157.

3.     NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells. DNA Cell Biol. 2020 Apr;39(4):513-521. 

4.     Down-regulation of CRTAC1 attenuates UVB-induced pyroptosis in HLECs through inhibiting ROS production. Biochem Biophys Res Commun. 2020 Oct 29;532(1):159-165.

5.     Rapid and semiquantitative detection of Staphylococcus epidermidis in humor samples by microfluidic platform. Sensors and Actuators B: Chemical, 2019. 278: 8-14.

Projects

1.     The regulatory role of FoxO3a pathway inhibition in the pathogenesis of age-related cataracts supported by National Natural Science Foundation of China. (2021-2024)

2.     The mechanisms and intervention study of Cartilage Acidic Protein 1(CRTAC1)n role in the onset of Age-related Cataract (ARC) by National Natural Science Foundation of China. (2018-2021)

3.     Shanghai Talent Development Fund supported by shanghai municipal human resources and social security bureau. (2018-2020)

4.     A role for mutant gammaS-crystallin in the organization of beaded filament structure protein/filensin in the formation of cataract by National Natural Science Foundation of China. (2014-2016)


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Dr. Ji conducts basic and clinical research in the areas of cataracts, including age-related cataracts and congenital cataracts.