Specialties & Service



The optometry and refractive surgery center of EENT Hospital commits to high quality treatment, compassionate patient care, and advanced vision research.

Our center leads research and clinical practice of corneal refractive surgery (RK, PRK, LASEK/Epi-Lasik, FLEX, SMILE, etc.), transepithelial rapid corneal cross-linking (CXL), ICL V4c, presbyopia correction in China. Our center ranks the top one in SMILE surgery volume globally, and ICL surgery volume in Chinese public hospitals. We have first reported the research results in term of SMILE-CCL, epikeratophakia with phototherapeutic keratectomy for the treatment of corneal dystrophy, and SMILE lenticule implantation for hyperopia, corneal ectasia, and keratoconus. Moreover, our hospital is the first one to establish High myopia and ICL clinic.

Also, we are the first one to elucidate the medical optometry concept, and launch the refractive development files for teen-agers and RGP research for the correction of refractive error. Furthermore, we have achieved remarkable results in terms of SOP for orthokeratology, RGP for keratoconus, and prevention and control of teen-agers myopia. In addition, our hospital is the pioneer to establish the mode of online training treatment for asthenopia, presbyopia, and children refractive error through the visual quality of physiology optical platform and binocular vision function research results.

Our center unites researchers from clinical team and NHC Key Laboratory of Myopia. We have won the second prize of national technical invention in the field of Ophthalmology & Optometry in China and the second prize of National Science and Technology Progress Award, the first prize of the Ministry of Education, Shanghai Science and Technology Progress Award and the Clinical Medical Achievement Award.


Our center consists of 6 professors/chief physicians, 8 deputy chief physicians, and more than 20 PhD doctors.

Clinical Services

We provide primary eye care and visual health care, and as well as expert care for refractive correction, including glasses, contact lenses or refractive surgery. Our clinical service also includes pre- and post-operative care to patients undergoing ophthalmological surgery and expert care for complex conditions.

Correction of refractive error  

Eyeglass prescriptions for patients with vision conditions such as nearsightedness, farsightedness, astigmatism, and presbyopia.

Refractive surgery

SMILE and FS-LASIK for correction of myopia and astigmatism

Surface ablation surgery LASEK and Trans-PRK

ICL procedure(V4c) for myopia and astigmatism

Accelerated transepithelial corneal cross-linking for keratoconus

Presbyopia correction surgery

Surgical treatment of complexed refractive problems

Contact lenses and Ortho-K

Prescription of RGP

Prescription of Ortho-K

Specialist clinic

Refractive error correction clinic

High myopia and ICL clinic

Corneal cross-linking for keratoconus clinic

Myopia control clinic

Contact lenses Clinic

Academic and Clinical Center

NHC Key Laboratory of Myopia (Fudan University) & Key Laboratory of Myopia, Chinese Academy of Medical Sciences

Shanghai Research Center of Ophthalmology and Optometry (SRCO)

Center of Intraocular lens Refractive Surgery

Shanghai Orthoketatology Study Group (SOS)

Asia-Pacific ICL Training Center for High Myopia

Asia-Pacific SMILE Training Center


We conduct basic and clinical research in the mechanism of myopia development and the treatment and control of myopia, with the goal of translating scientific research into advances in patient care.

Education & Training

Medical Student Education

MS degree program

PhD degree program

Post-doc program

Ophthalmology and Optometric Residency Training Program

Fellowship Program

Small incision lenticule extraction (SMILE) Training Courses

Intraocular lens Refractive Surgery Training Courses

Forefront Refractive Surgery Course: SMILE

Ortho-k and myopia control

Diagnosis and correction of presbyopia  

Contact Us

No. 19, Baoqing Road, Shanghai, China, 200031

Phone 86-21-64377134- 2914

No. 2600, Jiangyue Road, Shanghai, China, 201114

Phone 86-21-64377134- 3085

  • Contact Lens and Myopia Control Center
  • Center of Intraocular Lens Refractive Surgery

Myopia, also called nearsightedness, is associated with significant inconvenience and serious complications in high myopia cases. In the recent decade, myopia in children and adolescents has the characteristic of earlier onset, faster progression, and higher degree. The control of myopia progression in the young population would have remarkable impact on individual and society as a whole.

What is orthokeratology?

Modern myopic orthokeratology (ortho-k) lenses are reverse geometry rigid gas-permeable contact lenses that temporarily reshape the cornea during sleep and correct central myopic refractive error during waking hours without lenses. Aside from its effect on corneal refractive power, ortho-k has been reported to decrease axial elongation in children from previous clinical observations.

What is myopia control?

Myopia control is to monitor refractive development in children before myopia onset, and to use various methods to slow myopia progression and axial elongation after myopia onset. The well-recognized myopia control methods around the globe include but are not limited to orthokeratology, dual-focal or multi-focal soft contact lenses, atropine, specific spectacle lenses, etc.

Treatment offered:

Orthokeratology for myopia and astigmatism

RGP contact lens for regular and irregular corneas

Archiving of refractive development in children

Customized myopia control strategy

Our Team of Contact Lens Experts

Jiaqi Zhou, MD, PhD

Zhi Chen, MD, PhD

Feng Xue, MD

Li Zeng, MD

Selected publication of our team

1.Chen Z, Zhou J, Xue F, Qu X, Zhou X. The two-year add-on effect of using low concentration atropine in poor responders of orthokeratology in myopic children. Br J Ophthalmol, doi: 10.1136/bjophthalmol-2020-317980. Online ahead of print.

2.Zeng L, Chen Z, Fu D, Zhou J, Zhou X. Tear lipid layer thickness in children after short-term overnight orthokeratology contact lens wear. Journal of Ophthalmology. 2020; Article ID 3602653.

3.Chai Z, Zhou K, Yang J, Ma Y, Chen Z, Gao S, Liu J. Perceptual-assisted adversarial adaptation for choroid segmentation in optical coherence tomography. IEEE International Symposium on Biomedical Imaging (ISBI) 2020:https://ieeexplore.ieee.org/document/ 9098346.

4.Chai Z, Yang J, Zhou K, Chen Z, Zhao Y, Gao S, Liu J. Memory-assisted dual-end adaptation network for choroid segmentation in multi-domain optical coherence tomography. IEEE International Symposium on Biomedical Imaging (ISBI) 2021

5.Chen Z, Xue F, Zhou J, Qu X, Zhou X. Effects of orthokeratology on choroidal thickness and axial length. Optom Vis Sci 2016;93(9):1064-1071

6.Chen Z, Li T, Yao P, Xu Y, Zhou X. Effects of 0.05% racanisodamine on pupil size and accommodation. Optom Vis Sci 2010;87(12): 966-970

7.Chen Z, Niu L, Xue F, Qu X, Zhou Z, Zhou X and Chu R. Impact of pupil diameter on axial growth in orthokeratology. Optom Vis Sci 2012;89(11):1636-40.

8.Zhong Y, Chen Z, Xue F, Miao H, Zhou X. Central and peripheral corneal power change in myopic orthokeratology and its relationship with 2-year axial length change. Invest Ophthalmol Vis Sci 2015;56(8):4514-9.

9.Zhong Y, Chen Z, Xue F, Zhou J, Niu L, Zhou X. Corneal power change is predictive of myopia progression in orthokeratology. Optom Vis Sci 2014;91(4):404-11.

10.Liu G, Chen Z, Xue F, Li J, Tian M, Zhou X, Wei R. Effects of myopic orthokeratology on visual performance and optical quality. Eye Contact Lens 2018;44(5):316-321.

11.Chen Z, Xue F, Zhou J, Qu X, Zhou X, SOS Group. Prediction of orthokeratology lens decentration with corneal elevation. Optom Vis Sci 2017;94(9):903-7.

12.Chen Z, Zhou J, Qu X, Zhou X, Xue F, SOS Group. Effects of orthokeratology on axial length growth in myopic anisometropes. Cont Lens Anterior Eye 2018;41:263-6.

13.Chen Z, Zhou J, Xue F, Zhou X, Qu X. Increased corneal toricity after long-term orthokeratology lens wear. J Ophthalmol 2018 Article ID 7106028

14.Chen Z, Huang S, Zhou J, Qu X, Zhou X, Xue F. Adjunctive effect of orthokeratology and low dose atropine on axial elongation in fast-progressing myopic children – a preliminary retrospective study. Cont Lens Anterior Eye 2018 S1367-0484(18)30919-6

15.Chen Z, Jiang J, Xu J, Yang X, Yang Y, Wang K, Song H, Yang B, Cho P. Antibiotic eye drops prescription patterns by orthokeratology practitioners in China and the development of antibiotic usage guidelines. Cont Lens Anterior Eye. 2020 Aug 11:S1367-0484(20)30138-7. doi: 10.1016/j.clae.2020.07.005. Epub ahead of print. PMID: 32798156.


Center of Intraocular Lens Refractive Surgery is based on the NHC Myopia Key Laboratory, Shanghai Research Center of Ophthalmology and Optometry. The center established a clinical and research institute consists of medical service, education and research with the advantage of talents and technology. The center is the first specialist center applying intraocular lens to correct myopia in China. The center is also the education base of Asia-pacific ICL/TICL research.

In the center, every myopic patient, who is eager to remove spectacles and improve the life quality, can receive comprehensive ocular examinations and evaluations, customized designed surgical plan and intraocular lens, regular postoperative follow up, and multiple department diagnosis and therapy for myopia complications.

The center has a professional technical team consists of 6 professors/chief physicians, 8 associate chief physicians, more than 20 Ph.D doctors. The center also has experienced teams of examinations, surgery design, flow management and nursing. Most advanced medical devices such as Pentacam corneal tomophraphy, anterior segment OCT, wideangle fundus ophthalmoscopy, ultrasound biomicroscope, corneal specular microscopy and Hartmann-Shack wavefront aberrometer are applied in the assessment of the intraocular lens surgery.

The first central hole ICL /TICL V4c (Visian EVO ICL) in China was conducted in the center. The record of 154 surgeries on a single day and 110 surgery by a single surgeon is created and kept in the center. The surgeons invented a noval microsurgical technique of implantation without using an ophthalmic viscosurgical device. The center also dominated in formulating the Chinese Posterior Chamber Phakic Intraocular Lens Implantation Expert Consensus 2019. More than 30 sessions of ICL/TICL training courses have been held in the center. More than 500 ICL surgeons and technicians have been trained. Which greatly promoted the implication and development of intraocular lens technology in China. More than 20,000 cases of ICL/TICL/PRL/PR implantation have been conducted in the center and obtained the satisfaction rate of 99.4% in the patients.


ICL specialty clinic: Monday (pm), Pujiang District, Tuesday (pm), Baoqing District.